福利姬视频

Recent publications from ADASRI

Read the latest research, conference abstracts, standards, and patents brought to you by the 福利姬视频Science & Research Institute, LLC.

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Recent publications by topic

Infection control


Study finds that fewer than half of dental hygienists who left employment early in the pandemic returned to the workforce in 2021. | By Rachel Morrissey, JoAnn Gurenlian, Cameron Estrich, Laura Eldridge, Ann Battrell, Ann Lynch, Mikkelsen Matthew, Brittany Harrison, Marcelo Araujo, and Marko Vujicic


Study finds almost all surveyed dental hygienists (99.9%) from September 2020 to August 2021 reported COVID-19-specific infection prevention and control practices in place at their primary dental clinic. | By Cameron Estrich, JoAnn Gurenlian, Ann Battrell, Ann Lynch, Matthew Mikkelsen, Rachel Morrissey, Marko Vujicic, and Marcelo Araujo


Study finds that, as of August 2021, 75.4% of hygienists had been fully vaccinated against COVID-19, a higher proportion than the general public and health care workers overall outside dentistry at that time. | By JoAnn Gurenlian, Laura Eldridge, Cameron Estrich, Ann Battrell, Ann Lynch, Rachel Morrissey, Marcelo Araujo, Marko Vujicic, and Matthew Mikkelsen


Study describes process that dental instrument makers can use to develop and validate cleaning instructions for their reusable instruments. | By Prerna Gopal, Erin Claussen, Kristy Azzolin, and Spiro Megremis


A review summarizes the evidence of how SARS-CoV-2 infects the glands, oral mucosae, and saliva. | By Julie Teresa Marchesan, Blake M. Warner, and Kevin Byrd


Survey determines the cumulative prevalence and incidence rates of COVID-19 among dentists and assesses their level of engagement in specific infection control practices. | By Marcelo Araujo, Cameron Estrich, Matthew Mikkelsen, Rachel Morrissey, Brittany Harrison, Maria Geisinger, Effie Ioannidou, and Marko Vujicic


Study shows how SARS-CoV-2 infects cells in mouth, possibly leading to oral symptoms. | By Kevin Byrd et al.


A team of investigators present the first direct evidence that SARS-CoV-2 can infect and replicate in the cells of the mouth in humans, and that saliva is potentially infectious. | By Blake Warner and Kevin Byrd


Study estimates the prevalence of COVID-19 among US dental hygienists, describes infection prevention and control procedures, and identifies associated trends in mental health. | By Cameron Estrich, JoAnn Gurenlian, Ann Battrell, Sue Bessner, Ann Lynch, Matthew Mikkelsen, Rachel Morrissey, Marcelo Araujo, and Marko Vujicic


New bioactive composite not only has a low shrinkage stress, but also down-regulates the growth of oral biofilms, reduces acid production, maintains antibacterial activity after 90-day aging, and does not compromise cytocompatibility. | By Ghalia Bhadila, Deepak Menon, Xiaohong Wang, Taissa Vila, Mary Ann Melo, Silvia Montaner, Dwayne Arola, Michael Weir, Jirun Sun, and Hockin Xu


A new azo-type quaternary pyridinium salt helps reduce or prevent the build-up of potent antibacterial agents in the oral environment. | By Jirun Sun


Technical report provides guidance on the development of cleaning processes for dental instruments, and their validation, as one of the steps in a multi-step instrument reprocessing procedure. | By the 福利姬视频Standards Committee on Dental Products


Study generates the first integrated human oral single cell RNA sequencing atlases to predict cellular sources of susceptibilities to SARS-CoV-2 infection. | By Kevin Byrd et al.


Researchers conduct the first longitudinal study designed to track COVID-19 infection control practices and infection rates among US dentists. | By Cameron G. Estrich, Matthew Mikkelsen, Rachel Morrissey, Maria Geisinger, Effie Ioannidou, Marko Vujicic, and Marcelo Araujo


Risk analysis provides dental device manufacturers with information to better document cleaning procedures for their equipment. | By Kristy Azzolin


Study shows that a previously developed method, which was shown to be effective at detecting the cleanliness of artificially soiled dental instruments, was also effective at quantifying the cleanliness of clinically used dental instruments. | By Prerna Gopal, Erin Claussen, Satish Alapati, Mina Golubovich, Milica Novakovic, Jamie Spomer, and Spiro Megremis

Periodontics


Curcumin-loaded polymeric nanoparticles have antimicrobial and antibiofilm properties, with better effects when associated with blue light, being a promising therapy for preventing and treating peri-implant diseases. | By Caroline Coradi Tonon, Beatriz Panariello, Marlus Chorilli, Denise Madalena Palomari Spolidorio, and Simone Duarte


Low-temperature plasma effectively reduces peri-implantitis-related multispecies biofilms on titanium surfaces in vitro. | By Beatriz Panariello, Drashty Mody, George Eckert, Lukasz Witek, Paulo Coelho, and Simone Duarte


Simultaneous measurement of temperature and pH along with gingival sulcus depth may detect early signs of inflammation that current methods, such as probing and radiography, may not identify, thus minimizing potential tissue damage caused by periodontal disease. | By Nicole Ritzert, Asha Rani, Taejun Ko, Jeffrey Kim, and Shinae Kim


Review provides an overview of the toolkit available for diagnosing periodontal diseases, discusses commercially available options, and highlights the need for collaborative research initiatives and technology to overcome the challenges of rapid periodontal disease diagnosis. | By Taejun Ko, Kevin Byrd, and Shinae Kim


Proof-of-concept study opens venues in engineering high-resolution, implantable, and osteoconductive scaffolds with predetermined properties for bone regeneration. | By Yoontae Kim, Eun-Jin Lee, Albert Davydov, Stanislav Frukhtbeyen, Jonathan Seppala, Shozo Takagi, Laurence Chow, and Stella Alimperti


Review introduces the concept of the “gum–gut axis” as a framework for examining this reciprocal relationship between the periodontium and the gastrointestinal tract. | By Kevin Byrd and Ajay Gulati


Findings suggest that the mucosa-chip is a promising alternative to traditional platforms or assays to test a variety of biomaterials by offering a multi-layered tissue geometry, accessible layer-specific information, and higher sensitivity in detecting cellular responses. | By Khanh Ly, S. Ali Rooholghodos, Christopher Rahimi, Benjamin Rahimi, Diane Bienek, Gili Kaufman, Christopher Raub, and Xiaolong Luo


One common tissue engineering approach for regenerating or replacing damaged tissues involves a porous polymeric scaffold; this chapter discusses methods to evaluate cell distribution in the scaffolds using laser scanning confocal microscopy. | By Jirun Sun, Joy Dunkers, Sheng Lin-Gibson, and Nancy Lin


3D bicellular microphysiological models will be used as diagnostic tools for drug testing and identification of new targets involved in bone and craniofacial diseases. | By Eun-Jin Lee and Stella Alimperti


Electrochemical pH sensors aid in detecting inflammation and/or disease of oral tissues. | By Nicole Ritzert, Shinae Kim, and Asha Rani


By Stella Alimperti, Matthew Staymates, Thomas Hart, and Dana Graves


Study captures dynamic changes on epithelial barriers under inflammatory conditions that could potentially provide therapeutic targets against periodontal diseases. | By Styliani Alimperti

Pharmacology and therapeutics

(2024)
Non-opioid medications are first-line therapy for managing acute dental pain following tooth extraction(s) and the temporary management of toothache in adolescents, adults and older adults. | By Alonso Carrasco-Labra, Deborah Polk, Olivia Rose Urquhart, Tara Aghaloo, J. William Claytor, Vineet Dhar, Raymond A. Dionne, Lorena Espinoza, Sharon Gordon, Elliot Hersh, Alan Law, Brian S.-K. Li, Paul J. Schwartz, Katie J. Suda, Michael A. Turturro, Marjorie Lindsay Wright, Tim Dawson, Anna Miroshnychenko, Sarah Pahlke, Lauren Pilcher, Michelle Shirey, Malavika Tampi, Paul A. Moore

(2023)
A systematic review and meta-analysis of the literature on pharmacologic approaches to management of acute dental pain in children found that several over-the-counter medications used alone or in combination were seen to provide benefit. | By Anna Miroshnychenko, Maria Azab, Sara Ibrahim, Yetiani Roldan, Juan Pablo Diaz Martinez,Tamilselvan Tamilselvan, He Leon, Oliva Urquhart, Malavika Tampi, Deborah E. Polk, Paul A. Moore, Elliot V. Hersh, Alonso Carrasco-Labra, Romina Brignardello-Petersen.

Corticosteroids for managing acute pain subsequent to surgical extraction of mandibular third molars: A systematic review and meta-analysis (2023)
A systematic review and meta-analysis of the literature found trivial differences in postoperative pain when corticosteroids were administered orally, submucosally, or intramuscularly compared with a placebo in patients undergoing third-molar extractions.| By Anna Miroshnychenko, Maria Azab, Sara Ibrahim, Yetiani Roldan, Juan Pablo Diaz Martinez, Divyalakshmi Tamilselvan, Leon He, Olivia Urquhart, Francisca Verdugo-Paiva, Malavika Tampi, Deborah E. Polk, Paul A. Moore, Elliot V. Hersh, Romina Brignardello-Petersen, Alonso Carrasco-Labra

(2023)
Systematic reviews of the literature evaluated effectiveness of local anesthetics on acute dental in patients after tooth extraction and in patients with symptomatic irreversible pulpitis found that bupivacaine may be superior to lidocaine with epinephrine and mepivacaine; and that benzocaine may be superior to placebo for short term (20-30 minutes) relief of pain. | By Anna Miroshnychenko, Sara Ibrahim, Maria Azab, Yetiani Roldan, Juan Pablo Diaz Martinez, Divyalakshmi Tamilselvan, Leon He, Olivia Urquhart, Malavika Tampi, Deborah E. Polk, Paul A. Moore, Elliott V. Hersh, Alonso Carrasco-Labra, and Romina Brignardello-Petersen.

(2023)
A systematic review and network meta-analysis of risks and benefits of pharmacologic treatment for the management of acute postoperative pain following extraction of teeth in adults found that NSAIDs with or without acetaminophen result in better pain-related outcomes than opioids with or without acetaminophen (except acetaminophen 650 mg plus oxycodone 10 mg) or placebo. | By Anna Miroshnychenko, Sara Ibrahim, Maria Azab, Yetiani Roldan, Juan Pablo Diaz Martinez, Divyalakshmi Tamilselvan, Leon He, Joshua W. Little, Olivia Urquhart, Malavika Tampi, Paul A. Moore, Elliot V. Hersh, Bill Claytor, and Romina Brignardello-Petersen.

(2023)
Electronic surveys and small group engagement were used to elicit insight from study participants about relief of dental pain with respect with expected pain intensity. Although nonprescription and nonopioid pain relief options were preferred, willingness to accept opioid increased as expected pain levels increased, though mention of rescue analgesia as a third outcome could affect decision-making. | By Tim Dawson, Sarah Pahlke, Alonso Carrasco-Labra, and Deborah Polk.

(2023)
Non-opioid medications, specifically NSAIDs like ibuprofen and naproxen alone or in combination with acetaminophen, are recommended for managing acute dental pain after tooth extraction(s) and the temporary management of toothache in children. | By Alonso Carrasco-Labra, Deborah E. Polk, Olivia Urquhart, Deborah E. Polk, Olivia Urquhart, Tara Aghaloo, J. William Claytor, Vineet Dhar, Raymond A. Dionne, Lorena Espinoza, Sharon M. Gordon, Elliot V. Hersh, Alan S. Law, Brian S.-K. Li, Paul J. Schwartz, Katie J. Suda, Michael A. Turturro, Marjorie Lindsay Wright, Tim Dawson, Anna Miroshnychenko, Sarah Pahlke, Lauren Pilcher, Michelle Shirey, Malavika Tampi, and Paul A. Moore.


A survey of dental practitioners and periodontists assesses factors that affect antibiotic prescribing practices among the two groups. | By Effie Ioannidou, Nico Geurs, Ruth Lipman, Marcelo Araujo, Jay Elkareh, Steven Engebretson, Robert Eber, Thomas Oates, Patricia Diaz, and Catherine Spino


An analytical reaction–convection–diffusion model provides a useful platform for further exploration of electrode kinetics influenced by reaction-induced pH change. | By Brian Tackett, David Raciti, Nicholas Brady, Nicole Ritzert, and Thomas Moffat


Parylene-based flexible microelectrode patterns created by an inkjet printing technique could potentially find a myriad of applications in the field of neuroscience and brain-machine interfaces. | By Yoontae Kim, Stella Alimperti, Paul Choi, and Moses Noh 


Review offers a systematic approach to diagnose and manage commonly encountered oral manifestations of pediatric inflammatory bowel diseases. | By Muhammad Ali Shazib, Kevin Byrd, and Ajay Gulati 


Artificial blood vessel provides a methodology for investigating microvascular-related diseases. | By Paul Salipante, Steven Hudson, and Stella Alimperti


N-Acetyl cysteine is explored as a treatment for dental pulp whose growth has been arrested by toxic resin monomers in dental capping materials. | By Gili Kaufman and Drago Skrtic


Researchers explain how a better understanding of vasculature controls on bone development and homeostasis on normal and disease cases will facilitate the development of novel disease treatments that promote bone regeneration and remodeling. | By Eun-Jin Lee, Mahim Jain, and Stella Alimperti


Current state-of-the-art research on insulator-based dielectrophoresis systems is reviewed, and potential future work is highlighted. | By Prateek Benhal, David Quashie, Yoontae Kim, and Jamel Ali 


Survey evaluates dentists’ habits and uses of antibiotics in treating endodontic infections. | By Rashad Vinh, Ana Bedran-Russo, Jamie Spomer, Olivia Urquhart, and Marcelo Araujo


Researchers develop drug delivery systems that could be useful for the targeted treatment of bacteria or diseases that produce acid or generate local acidic environments. | By Xiaohong Wang, Han Byul Song, Vivek Prabhu, Yun Liu, and Jirun Sun


A new two-step treatment reduces dentin sensitivity. | By Laurence Chow, Antony Giuseppetti, and Shozo Takagi


Results could assist in developing improved dentin desensitization and other remineralization treatments. | By Shozo Takagi, Eaman Karim, and Laurence Chow


Study finds that antibiotic prescribing by dentists has significantly declined in the past 15 years, although prescriptions for fewer than five days have increased since 2010. | By Cameron Estrich, Ruth Lipman, and Marcelo Araujo


Scientific research review of the evidence concludes HPV vaccines are safe, effective and efficacious. | By Alessandro Villa, Lauren Patton, Anna Giuliano, Cameron Estrich, Sarah Pahlke, Kelly O’Brien, Ruth Lipman, and Marcelo Araujo


Policy-making


Bruno Fernandes Matuck, Luiz Fernando Ferraz da Silva, Blake M. Warner, Kevin Matthew Byrd


Article provides a brief overview of strategies that can be used to overcome common challenges to guideline adoption. | By Julie Frantsve-Hawley, Elliot Abt, Alonso Carrasco-Labra, Tim Dawson, Maria Michaels, Sarah Pahlke, Brad Rindal, Heiko Spallek, and Robert Weyant


Article covers the use of scientific research to establish specifications and standards used to evaluate dental materials and products, and how a practitioner can use these standards to ensure the safety and performance of the materials that they use in their everyday practice. | By Spiro Megremis


Study assesses the prevalence of anxiety and depression symptoms among dental health care workers during the COVID-19 pandemic. | By Laura Eldridge, Cameron Estrich, JoAnn Gurenlian, Ann Battrell, Ann Lynch, Marko Vujicic, Rachel Morrissey, Stacey Dershewitz, Maria Geisinger, and Marcelo Araujo


Commentary argues scientists must develop strategies for communicating clearly and concisely to refute misinformation and disinformation. | By Michael Glick, Mark Wolff, and Alonso Carrasco-Labra


A look at how clinicians must understand the implications of a guideline's recommendations, assess the trustworthiness of the guideline development process, and evaluate the extent to which the recommendations are applicable to patients in their practice settings. | By Romina Brignardello-Petersen, Alonso Carrasco-Labra, and Gordon Guyatt


ADASRI researchers argue that dental professionals' adherence to strict guidelines throughout the pandemic has paid off in current health policies that commend their efforts. | By Cameron Estrich and Marcelo Araujo


Machine learning techniques are explored as a way to make the process of writing systematic reviews more efficient and less prone to error. | By Alonso Carrasco-Labra, Olivia Urquhart, and Heiko Spallek


Book chapter addresses how to formulate a clinical query to perform a thorough literature search and assess the trustworthiness and reliability of the available evidence to enhance patient care. | By Alonso Carrasco-Labra, Malavika Tampi, Olivia Urquhart, Scott Howell, Austin Booth, and Michael Glick


Evidence suggests that teledentistry, particularly mHealth (messages and apps), is a promising clinical tool for preventing and promoting oral health, especially under the accelerated virtualization of dentistry. | By Constanza Fernandez, C.A. Maturana, S.I. Coloma, Alonso Carrasco-Labra, and Rodrigo Giacaman


Study provides insights on dental hygienists’ employment patterns as well as their attitudes toward working as dental hygienists during a pandemic. | By JoAnn Gurenlian, Rachel Morrissey, Cameron Estrich, Ann Battrell, Sue Bessner, Ann Lynch, Matthew Mikkelsen, Marcelo Araujo, and Marko Vujicic  


Researchers propose novel approaches to communicating harm outcomes for expert panels to consider when developing clinical practice guidelines. | By Lauren Pilcher, Malavika Tampi, Olivia Urquhart, and Alonso Carrasco-Labra


Framework harmonizes individual- and population-level perspectives for the development of oral health policies. | By Malavika Tampi, Olivia Urquhart, Lauren Pilcher, Sarah Pahlke, and Alonso Carrasco-Labra


Researchers call for investments in well-conducted primary studies including patient-important oral health outcomes and perspectives. | By Sarah Pahlke, Malavika Tampi, Lyubov Lytvyn, Lauren Pilcher, Olivia Urquhart, and Alonso Carrasco-Labra


By Alonso Carrasco-Labra

Preventive dentistry


The surface roughness of the retainer material plays a significant role in the ability of cleaning solutions to remove stains, demonstrating a greater effect on cleaning rough specimens with respect to improvements in light transmittance and greater changes in color. | By Laurie Susarchick, Insia Virji, Grace Viana, Mervat Mahmoud, Veerasathpurush Allareddy, Max Gruber, Henry Lukic, Spiro Megremis, and Phimon Atsawasuwan


Computational solutions have a high accuracy in predicting tooth loss; however, they also display a high risk of bias. | By Akira Hasuike, Taito Watanabe, Shin Wakuda, Keisuke Kogure, Ryo Yanagiya, Kevin Byrd, and Shuichi Sato


Paper outlines directions for using single-cell and spatial multiomics approaches to create the first ever map of oral and craniofacial cells, which will lead to future innovations in the treatment of common and rare diseases. | By Ana Caetano, Ines Sequeira, and Kevin Byrd


Maintaining optimal oral health may help reduce the need for urgent preradiotherapy dental treatment, potentially reducing the risk of osteoradionecrosis of the jaw and minimizing delay of oncologic treatment in patients with head and neck cancer. | By Olivia Urquhart, Hillary DeLong, Kathleen Ziegler, Lauren Pilcher, Sarah Pahlke, Malavika Tampi, Kelly O’Brien, Lauren Patton, Nishant Agrawal, Theresa Hofstede, Deepak Kademani, Mark Lingen, Nathaniel Treister, C. Jillian Tsai, Alonso Carrasco-Labra, and Ruth Lipman


Study demonstrates that the heating conditions of the e-cigarette change the physicochemical properties of the aerosols and their metal contents, thereby possibly affecting users’ oral and respiratory systems. | By Taejun Ko and Shinae Kim


Fluorescence, visual or visual-tactile classification systems, imaging, transillumination and optical coherence tomography, and electrical conductance or impedance technologies are evaluated for their ability to detect and diagnose caries. | By Tanya Walsh, Richard Macey, David Ricketts, Alonso Carrasco Labra et al.
 


Novel sealant is promising to inhibit caries and promote the remineralization of enamel and dentin. | By Xiuzhi Fei, Yuncong Li, Michael Weir, Bashayer Baras, Haohao Wang, Suping Wang, Jirun Sun, Mary Melo, Jianping Ruan, and Hockin Xu


Applying protein repellents to restorations could help slow the formation of biofilm and associated oral diseases, researchers argue. | By Leopoldo Torres Jr. and Diane Bienek


Researchers argue there is a need to improve the methodological standards and increase consistency in the way caries risk prediction models are developed and evaluated. | By Margherita Fontana, Alonso Carrasco-Labra, Heiko Spallek, George Eckert, and Barry Katz


Researchers review the impact of e-cigarettes on oral health, dentistry's role in smoking cessation and the need to address gaps in vaping research. | By Purnima Kumar, Maria Geisinger, Hillary DeLong, Ruth Lipman, and Marcelo Araujo


Study tests whether charcoal-containing fluoride dentifrices have at least 90% of the labeled amount of fluoride available and whether charcoal-containing dentifrices were effective against Streptococcus mutans. | By Christina Tyrakowski, Erin Claussen, Prerna Gopal, and Jamie Spomer


Study describes the development of a clinically relevant antimicrobial susceptibility test for antiplaque and antigingivitis products by mimicking the oral environment. | By Erin Claussen, Prerna Gopal, and Jamie Spomer

Restorative dentistry

 | By Yifeng Liao, Max Gruber, Henry Lukic, Jim McLees, Si Chen, Alan Boghosian, and Spiro Megremis

 | By Lauren Pilcher, Sarah Pahlke, Olivia Urquhart, Kelly K. O鈥橞rien, Vineet Dhar, Margherita Fontana, Carlos Gonz谩lez-Cabezas, Martha Ann Keels, Ana Karina Mascarenhas, Marcelle M. Nascimento, Jeffrey A. Platt, Gregory J. Sabino, Rebecca L. Slayton, Norman Tinanoff, Douglas A. Young, Domenick T. Zero, Malavika P. Tampi, DeVonna Purnell, Josefina Salazar, Spiro Megremis, Diane Bienek, and Alonso Carrasco-Labra 

 | By Lauren Pilcher, Sarah Pahlke, Olivia Urquhart, Kelly O鈥橞rien, and Alonso Carraso-Labra


Blue light activation of a novel dental resin reduces presence of Streptococcus mutans. | By Patricia Comeau, Beatriz Panariello, Simone Duarte, and Adriana Manso


New cement may potentially enhance the longevity of fixed dental restoration through its excellent mechanical properties, low shrinkage stress, and strong antibacterial properties. | By Rashed Alsahafi, Xiaohong Wang, Heba Mitwalli, Abdullah Alhussein, Abdulrahman Balhaddad, Mary Anne Melo, Thomas Oates, Jirun Sun, H. K. Xu, and Michael Weir


Novel primer achieves improved dentin infiltration and bonding strength, suggesting significant potential for further developing dental restorative materials with extended service life. | By Xiaohong Wang and Shinobu Yamauchi


Carbonate-containing hydroxyapatite synthesized via calcium phosphate cement proves to be a promising substrate for electron paramagnetic resonance-based dosimetry. | By Eaman Karim, Veronika Szalai, Lonnie Cumberland, Alline Myers, Shozo Takagi, Stanislav Frukhtbeyn, Ileana Pazos, and Laurence Chow


Study develops an antibacterial, remineralizing, and low-shrinkage-stress composite. | By Hanan Filemban, Ghalia Bhadila, Xiaohong Wang, Mary Ann Melo, Thomas Oates, Gary Hack, Christopher Lynch, Michael Weir, Jirun Sun, and Hockin Xu


Method may pave the way to engineer 3-D bone scaffolds with controlled hydroxyapatite composition and pre-defined properties, which will enhance graft-host integration in various anatomic locations. | By Yoontae Kim, Eun-Jin Lee, Anthony Kotula, Shozo Takagi, Laurence Chow, and Stella Alimperti


Of the 387 respondents, 83.7% stated that they repair defective restorations, and 16% stated that they always replace them. | By Wafaa Kattan, Olivia Urquhart, Carissa Comnick, Michelle McQuistan, Sandra Guzm谩n-Armstrong, Justine Kolker, and Erica Teixeira


Researchers develop a novel low-shrinkage-stress, antibacterial, and remineralizing resin composite to address dental composite restoration failure caused by recurrent caries at the margins. | By Hanan Filemban, Ghalia Bhadila, Xiaohong Wang, Mary Ann Melo, Thomas Oates, Michael Weir, Jirun Sun, and Hockin Xu


Fluorescence lifetime imaging microscopy is discussed for its potential to provide unique insights into the structure-property relationships of dental composites. | By Quinn Easter 


The hodograph equation proves sufficiently flexible for a reliable description of all nonlinearities of the kinetic curves predicted in molecular dynamics simulations of chromium and silicon. | By Eaman Karim, Miao He, Ahmed Salhoumi, Leonid Zhigilei, and Peter Galenko


An objective and nationally representative rate of amalgam-restored caries for the US population is calculated for the first time. | By Cameron Estrich, Ruth Lipman, and Marcelo Araujo


Proof-of-concept study opens venues in engineering high-resolution, implantable, and osteoconductive scaffolds with predetermined properties for bone regeneration. | By Yoontae Kim, Eun-Jin Lee, Albert Davydov, Stanislav Frukhtbeyen, Jonathan Seppala, Shozo Takagi, Laurence Chow, and Stella Alimperti 


A novel bioactive nanocomposite was developed with low shrinkage stress, strong antibiofilm activity, and high levels of ion release for remineralization, without undermining the mechanical properties and degree of conversion. | By Ghalia Bhadila, Xiaohong Wang, Michael Weir, Mary Ann Melo, Frederico Martinho, Guadalupe Garcia Fay, Thomas Oates, Jirun Sun, and Hockin Xu


A covalent adaptable network with high glass transition temperature, superior mechanical properties including toughness and ductility, and unprecedented spatio鈥恡emporally controlled dynamic behavior is prepared. | By Nancy Sowan, Han-Byul Song, Lewis Cox, James Patton, Benjamin Fairbanks, Yifu Ding, and Christopher Bowman 


Simulations reveal that, for chromium and nickel, vacancy concentrations produced during crystallization can exceed the equilibrium values at corresponding temperatures by orders of magnitude. | By Miao He, Eaman Karim, Maxim Shugaev, and Leonid Zhigilei 


New composite could inhibit recurrent caries at restoration margins by reducing polymerization stress and protecting enamel hardness. | By Ghalia Bhadila, Xiaohong Wang, Wen Zhou, Deepak Menon, Mary Ann Melo, Silvia Montaner, Thomas Oates, Michael Weir, Jirun Sun, and Hockin Xu


New bioactive nanocomposite has the potential to suppress recurrent caries at restoration margins, protect tooth structures and increase restoration longevity. | By Ghalia Bhadila, Hanan Filemban, Xiaohong Wang, Mary Ann Melo, Dwayne Arola, Franklin Tay, Thomas Oates, Michael Weir, Jirun Sun, and Hockin Xu


Novel sensors can send early warning signals before an implant fails. | By Jeffrey Kim, Gery Stafford, Carlos Beauchamp, and Shinae Kim


Study determines the impact of triethyleneglycol dimethacrylate on the ability of dental pulp stem cells to maintain their self-renewal capabilities, develop and preserve their 3-D structures and deposit tertiary dentin. | By Gili Kaufman, Naima Makena Kiburi, and Drago Skrtic 


Study proposes an alternative solution to help the dental community examine and comprehend fracture behaviors of zirconia dental ceramics used to restore damaged teeth. | By Yifeng Liao, Max Gruber, Henry Lukic, Si Chen, and Spiro Megremis


Study evaluates novel antimicrobial copolymers to help yield dental restoratives with well-controlled biofunction. | By Diane Bienek, Anthony Giuseppetti, Ugochukwu Okeke, Stanislav Frukhtbeyn, Peter Dupree, Sharukh Khajotia, Fernando Esteban Florez, Rochelle Hiers, and Drago Skrtic


A computer-controlled method may be used for making dental devices for dental restorative material, denture, orthodontic treatment, dental implant, implant, tissue regeneration, and tissue engineering. | By Jirun Sun and Young Lee


Researchers argue CHA cements could be used as electron paramagnetic resonance (EPR) calibration references and dosimeters. | By Eaman Karim, Lonnie Cumberland, Shozo Takagi, Stanislav Frukhtbeyn, Ileana Pazos, and Laurence Chow 


Study measures the physical and thermal behavior of four commercially available orthodontic materials. | By Henry Lukic, Raquel Miera, and Spiro Megremis


Lab-made monomers and polymers capable of switching physicochemical properties in response to pH variations in oral environments could become a new class of dental restoratives. | By Han Byul Song, Xiaohong Wang, Sara Orski, Kathryn Beers, and Jirun Sun


New antimicrobial monomers are expected to yield a new class of restoratives with both antimicrobial and remineralizing capabilities. | By Diane Bienek, Anthony Giuseppetti, Stanislav Frukhtbeyn, and Drago Skrtic


A pH-sensitive quaternary pyridinium salt could minimize tooth fracture and microleakage in dental restorations. | By Jirun Sun, Ethan Finley, and Xiaohong Wang


Novel methacrylate analogs of antimicrobial quaternary ammonium salts functionalized with carboxylic groups increased the shear bond strength of dental restorations and exhibited satisfactory biocompatibility. | By Anthony Giuseppetti, Peter Dupree, Stanislav Frukhtbeyn, Leopoldo Torres, and Diane Bienek


The flower enhances resin adhesion to dentin. | By Ariene Leme-Kraus, Mariana Cavalcante Dos Reis, Bin Zhou, Yvette Alania, Shao-Nong Chen, Guido Pauli, and Ana Bedran-Russo


Study authenticates the dental pulp / extracellular matrix platform as an efficient tool for validating the impact of molecules to restore mineral deposition in compromised tissue and maintain reparative dentin formation. | By Gili Kaufman, Anthony Kotula, William Jones, and Fjorela Xhyliu


Novel material exhibits anti-inflammatory, anti-microbial and osteogenic properties needed for the next generation of dental and bone restoration. | By Stanislav Frukhtbeyn, Michael Valerio, Jeffrey Kim, and Gili Kaufman


Study investigates an alternative method for measuring the mechanical performance of zirconia dental ceramics. | By Yifeng Liao, Max Gruber, Henry Lukic, and Spiro Megremis


Researchers determine the kinetics of tetragonal-to-monoclinic transformation in 3Y-TZP powder via hydrothermal treatment. | By Max Gruber, Yifeng Liao, and Spiro Megremis


Novel adhesives demonstrate potential in developing dental restorations with extended service life and may find wider dental applications and broader utility in medical device development. | By Shinobu Yamauchi, Xiaohong Wang, Hiroshi Egusa, and Jirun Sun